Polycystic Ovarian Syndrome (PCOS)
- Why does PCOS lead to threatened early miscarriage?
PCOS is mainly caused by the development of excessive testicular tissues in the ovaries. These testicular tissues will secrete a surplus amount of androgen and with that, multiple ovarian follicles will be developed simultaneously (normally, only one ovarian follicle will be developed monthly). Having multiple follicles developing at the same time will mean that the body will not have enough nutrients to ensure that all follicles are sufficiently nourished. This will affect the quality of the eggs and inhibit the maturation of the eggs, delaying ovulation. Delayed ovulation will disrupt the luteal phase, resulting in a luteal phase defect and low levels of progesterone.
- Treatment of threatened early miscarriage caused by PCOS:
Apart from supplementing progesterone, Antai hospital treats PCOS by tackling the root cause and remove the testicular tissues via a 3D laparoscopic surgery.
Primary Ovarian Insufficiency (POI)
- Why does POI lead to threatened early miscarriage?
With POI, your endometrium inner lining will be thinner because of low estrogen levels. You will also not be able to release a mature egg each month and even if the egg is released, it is most likely of a poor quality. Because of irregular ovulation, the formation of corpus luteum will be affected hence producing low levels of progesterone. With thinner endometrium lining and low levels of progesterone, it is very difficult to have proper implantation that is secure, and the risk of miscarriage is extremely high.
- Treatment of threatened early miscarriage caused by POI:
Likewise, the best way to prevent a threatened early miscarriage caused by POI is supplementing the progesterone level. This is very important for patients with POI because not only is their progesterone level low, but their endometrium lining is also thin, making it doubly hard for the implantation to be secure. By right, POI should be treated before pregnancy by increasing the ovarian functions by allowing the ovaries to “rest” with birth control pills for a few months.
Ovarian Dermoid Cyst
- Why does ovarian dermoid cyst lead to threatened early miscarriage?
Since the dermoid cyst is grown in the ovaries, it will affect the ovarian functions such as secreting endocrines and ovulating. With abnormal endocrine secretion and disrupted ovulation, your eggs will be of poor quality leading to luteal phase defect and low levels of progesterone.
- Treatment of threatened early miscarriage caused by ovarian dermoid cyst:
Before supplementing progesterone, patients will have to remove the dermoid cyst under a 3D laparoscopy. hCG does not need to be supplemented because the hCG levels should rise naturally if the progesterone treatment is working.