PCOS: Is it a congenital condition?
Introduction
Polycystic ovary syndrome (PCOS) is considered the most common endocrine disorder in females, especially in women of reproductive age. The worldwide prevalence of PCOS is estimated to be 5–10%. PCOS could be diagnosed by infertility, acne, amenorrhea or oligomenorrhea, hirsutism, insulin resistance, obesity, hyperandrogenism, and polycystic ovaries by ultrasonography. Association of PCOS with infertility is well studied and is thought to be responsible for 40% of female infertility. Moreover, it is a leading cause of endometrial carcinoma. Besides reproductive abnormalities, PCOS is also strongly associated with a wide range of metabolic disorders, such as hepatic steatosis, glucose intolerance, dyslipidemia, diabetes mellitus type II (T2DM), and hypertension.
Classification of Types of PCOS:
- Chronic Endocrine Imbalance – PCOS
- Metabolism Disorder – PCOS
- Multi-Organ Malformation – PCOS
- Behavioural Abnormality – PCOS
Cause
PCOS has been identified to have abnormality within the ovaries of these patients. A common factor that they all share, is the presence of intrinsic ovarian factors, the testosterone-secreting tissues within the ovaries, known as Leydig cells or even Theca cells. PCOS is considered a congenital condition, because these abnormal cells are not completely eliminated during embryogenesis, which results in the babies already born with these traces within their ovaries. The cause however, with our understanding and research at Antai Hospital, is due to certain environmental factors causing a mutation or affecting the embryogenesis process.
There have been several studies showcasing that they failed to find a fully penetrant variant. Thus, we believe that PCOS is not an inherited condition, but more of an environmentally induced disorder during embryogenesis.
Symptoms
- Metabolic disorders
- Diabetes Type II
- Amenorrhea
- Missed Periods
- Hirsutism
- Acne
- Patches of dark pigmentation on skin
- Rough hair
- Obesity
- Pelvic Pains
- Difficult in conceiving
- Recurrent Miscarriage
Diagnosis for PCOS
For a condition such as PCOS that has several overlapping symptoms, misdiagnosis is bound to occur. Differential diagnosis and specific assessments must be conducted to accurately diagnose PCOS.
- Ultrasound of the ovarian follicles
- Laparoscopic examination of the ovaries
- Blood Profile
- Hormonal Profile (Testosterone)
Treatment For PCOS At Antai Hospital
Antai Hospital opts for an effective minimally invasive surgical procedure that extracts all abnormal Leydig cells within the ovaries using 3D Laparoscopy. Upon recovery, patients can observe restoration of a healthy menstrual cycle, and a balanced hormonal profile, with the physical symptoms dissipating as well. A pregnancy can now be achieved healthily and naturally.
Note:
If a patient has other pre-existing conditions or complications, treatment for those factors are required as well to achieve a successful pregnancy. Diagnosis and treatment comprehensively is key to achieving this.
Antai Hospital’s Commitment
Antai Hospital’s full refund policy for the miscarriage prevention treatments we provide should already be the best guarantee for a healthy pregnancy. Patients should rest assured, can and should go about their everyday life, focusing their diet on vegetables, beans, celery, and other fiber-rich foods. Besides that, an active lifestyle of yoga and swimming should also be incorporated to help relieve stress and increase blood circulation, which is beneficial for the fetus’s development and the mother’s health. With our assurance, a healthy lifestyle, and peace of mind, you can go through a healthy pregnancy with no complications.
Recurrent miscarriages are no doubt a heavy blow to the patient’s physical and mental health. All we can do is to help ease the burden and decrease your trauma, to slowly help you overcome the anxiety with the love and care that we provide at Antai Hospital.
Trust in Antai Hospital and trust in yourself, your pregnancy is our priority.