Parental Chromosomal Abnormality & Miscarriage – Antai Hospital

Parental Chromosomal Abnormality does not cause embryonic demise

There are 3 types of genetic mutation that may occur during the development of a newly fertilized embryo during your pregnancy:

  • Lethal mutation
  • Deformity-causing mutation
  • Carrier mutation

The first 2 types of mutations are congenital anomalies, which means they cannot be inherited and caused by the changes or abnormalities of the environmental factors (internal and external). They have nothing to do with the chromosomal abnormalities of the parents, because these mutations are not inherited from them. The embryo perishes due to the genetic instability or lack/excess genetic information caused by the mutations, leading to an inevitable embryonic demise.

The only genetic mutation an embryo may inherit from its parent’s is the 3rd type which is Carrier Mutation.

What is a lethal mutation?

A lethal mutation is also known as a lethal allele that causes the death of the embryo or fetus that carries or develops such mutations. Depending on the gene or genes involved, lethal alleles might be recessive, dominant, or conditional. Lethal alleles can kill an organism before birth or at any point after birth, though they usually show up early in development. It is unlikely that parents can transfer such mutations to their offspring, as they are caused by negative factors (internally or externally) during embryogenesis. Furthermore, you will not have these mutations in your genes if you believe you are passing them down to your child.

What is a Deformity-Causing Mutation?

The deformity causing mutations are mutations that cause congenital defects in the newborn. Having too few or too many chromosomes, or structural issues with the chromosomes can lead to conditions such as Down’s Syndrome, Klinfelter syndrome, Turner’s Syndrome etc. A single gene defect can also cause abnormalities. These form of mutations are rarely inherited as they are sex chromosomes abnormalities, and can cause universal infertility in people who carry these mutations. Your newborn develops these mutations due to environmental factors, including age, drugs, alcohol or disease of the mother during pregnancy.

What is a Carrier Mutation?

A carrier mutation is a mild chromosomal mutation, where the chromosomes are expressed in gene translocation and inversion, meaning they have different dispositions of chromosomes. Parents can pass on this type of mutation to their offspring for many generations. 

However, this mutation does not cause any lack of genetic information which is why the most individuals with these mutations continue towards a successful pregnancy and give birth to healthy children. 

Genetically, these offspring may appear different than the norm, but on the outside, they are perfectly fine and capable of leading normal and healthy lives.

If they were truly some genetic faults in the sperm cells and egg cells from the parents, the embryo will not sustain long after a very unlikely fertilization. 

Misconception amongst patients and doctors alike

This is a widely held misconception by patients and even medical professionals, that believe the genetic abnormality of the parents is the primary cause of embryonic demise and their recurrent miscarriage. Leading many couples to believe they are untreatable and cannot have children.

Antai Hospital has determined that the real cause behind a genetic mutation is the aforementioned: Environmental factors, and we provide effective diagnostics and treatment for it, to prevent future embryonic or fetal demise and recurrent miscarriages. Couples should come to Antai Hospital and receive the necessary treatments, and rest assured you can have a successful pregnancy very soon and have healthy children of your own.

Antai Hospital’s Commitment

Antai Hospital’s full refund policy for the miscarriage prevention treatments we provide should already be the best guarantee for a healthy pregnancy. Patients should rest assured, can and should go about their everyday life, focusing their diet on vegetables, beans, celery, and other fiber-rich foods. Besides that, an active lifestyle of yoga and swimming should also be incorporated to help relieve stress and increase blood circulation, which is beneficial for the fetus’s development and the mother’s health. With our assurance, a healthy lifestyle, and peace of mind, you can go through a healthy pregnancy with no complications.

Recurrent miscarriages are no doubt a heavy blow to the patient’s physical and mental health. All we can do is to help ease the burden and decrease your trauma, to slowly help you overcome the anxiety with the love and care that we provide at Antai Hospital.

Trust in Antai Hospital and trust in yourself, your pregnancy is our priority.

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