Corpus Luteum Insufficiency and Recurrent Miscarriage
Corpus luteum insufficiency is when the corpus luteum in the ovaries is underdeveloped and does not produce enough progesterone.
Corpus luteum insufficiency will affect:
- the thickening of the endometrial wall and,
- the development and growth of the fetus during your early pregnancy (0-3 months).
Corpus luteum insufficiency has two main characteristics during early pregnancy:
- low levels of progesterone
- low levels of HCG
If left untreated, it will lead to a threatened miscarriage and recurrent immunological miscarriage. Antai Hospital is the only private hospital that offers contractual recurrent miscarriage treatment with a full refund policy.
How does Corpus Luteum Insufficiency cause recurrent miscarriage?
During normal ovulation, the ovarian follicles release a mature oocyte from the ovaries for fertilization. The remainder of the follicle will develop into the corpus luteum.
The corpus luteum plays a crucial role in maintaining healthy pregnancies. It secretes the hormone Progesterone, making the endometrium wall more vascular and thickened, preparing it for a potential pregnancy.
If the corpus luteum is underdeveloped, it will not produce enough progesterone and can lead to complications such as:
- The embryo is unable to make healthy implantation due to the thin endometrium.
- Restricted development for the embryo and fetus
Both complications will lead to recurrent early miscarriage or fetal demise.
What are the causes of Corpus Luteum Insufficiency?
A multitude of conditions can cause corpus luteum insufficiency, but the following three factors are the primary causes behind its underdevelopment:
- Premature Ovarian Insufficiency (POI)
- Polycystic Ovarian Syndrome (PCOS)
- Endometriosis
Symptoms
Symptoms of corpus luteum insufficiency include the symptoms of POI, PCOS, and Endometriosis. They include:
- Hot flashes or night sweats
- Mood swings
- Acne on the back and facial areas
- Obesity
- Excessive body hair
- Painful menses that increase in severity and flow over time
You may have a risk of developing corpus luteum insufficiency if you have a history of:
- Recurrent miscarriages or induced abortions
- Painful menstruation (caused by Endometriosis)
- Infertility
- Infrequent menstrual periods (月经稀发)
Diagnosis
- B-scan to check for chocolate cyst in the ovaries.
- B-scan to check for polycystic ovaries.
- A hormonal blood test to determine levels of your reproductive hormones (FSH, Estrogen, Testosterone, Progesterone; additional HCG test if you are pregnant)
- Test for the presence of anti-embryonic antibodies.
Corpus luteum insufficiency may be caused by one, two, or all three factors (POI, PCOS and Endometriosis), depending on your diagnosis.
Treatment
To effectively treat corpus luteum insufficiency, Antai Hospital will first need to treat the root causes before administering our specialized progesterone-supplement treatment via injections.
Your treatment will depend on which of the conditions you currently belong to:
- If you are not yet pregnant (before pregnancy), Antai Hospital will administer the following effective treatments depending on the conditions you are diagnosed with.
- Treatment of POI:
Using contraceptives to help the ovaries recover their healthy functions. Read more here.
- For the treatment of PCOS:
The surgical removal of testicular tissues (Leydig cells) from the ovaries. Read more here.
- For the treatment of Endometriosis:
Using 3D- laparoscopy to remove chocolate cysts and excise lesions. Read more here.
- Immunological factor
If you test positive for anti-embryonic antibodies, Antai will administer its patented immunotherapy that effectively prevents recurrent immunological miscarriage.
- If you are currently pregnant, Antai Hospital will directly
- Administer progesterone supplementary treatment to boost your progesterone to levels to healthy conditions.
- Supplement any other insufficient pregnancy hormones (Thyroid hormones, estrogen, PLT, etc.) to healthy levels, to sustain a healthy pregnancy.
- If you test positive for anti-embryonic antibodies, Antai will administer its patented immunotherapy that effectively prevents recurrent immunological miscarriage.
Antai Hospital offers highly effective recurrent miscarriage treatment with a full refund policy. If you are interested in finding out more, please arrange a consultation with us today.
Trust in Antai Hospital and trust in yourself, your pregnancy is our priority.