Title: Hyperthyroidism and Corpus Luteum Insufficiency
The thyroid glands play an essential role in the regulation of metabolism via the secretion of 2 crucial hormones:
- T3, also known as triiodothyronine
- T4, also known as thyroxine
Hyperthyroidism is an endocrine disorder where the thyroid glands secrete an excess amounts of thyroid hormones (T3 and T4). If left untreated, Hyperthyroidism can cause pregnancy loss, fetal demise, and, eventually, recurrent miscarriages.
It is commonly caused by an autoimmune disease known as Grave’s disease. (坟墓病)
If you have a history of the following, you may have Hyperthyroidism:
- Recurrent miscarriage
- Shortened menstrual period (distinct symptom)
- Intolerance to heat
- Mood swings
- Weight-loss
- Increase in basal metabolism
If left untreated, it will lead to a early miscarriage, fetal demise and recurrent immunological miscarriage. Antai Hospital is the only private hospital that offers contractual recurrent miscarriage treatment with a full refund policy.
How does Hyperthyroidism affect the Menstrual Cycle?
The function of your thyroid gland is to keep your boy’s metabolic processes and function up-and-running and in balance. Its 4 main functions are:
- Metabolism
- Cardiovascular
- Growth & Development
- Maintenance of sexual function
Examples of process affected by thyroid hormones include:
- Breathing
- Heart rate
- Menstrual Cycle (accelerates the menstrual cycle)
- Bone Development
- Body Temperature
- Muscle Development
In the case of hyperthyroidism, the excess amount of T3 and T4 in the blood stimulates and accelerates all metabolic processes of the body. In the menstrual cycle, the development processes of the egg cells and corpus luteum are accelerated in the ovaries.
This leads to an increase in the rate of ovulation, a shorter luteal phase and corpus luteum insufficiency.
How does Hyperthyroidism cause Corpus Luteum Insufficiency?
For women who have Hyperthyroidism, the two most common and distinct symptom is:
- The shortening of your menstrual period
- Increase in menstrual flow
Due to high T3 and T4 in the body, all bodily metabolism aspects are accelerated, including the menstruation cycle. A shorter menstrual period means the corpus luteum has insufficient time to fully mature and develop, directly leading to corpus luteum insufficiency.
As we all know, Progesterone is a crucial hormone that is needed to sustain a healthy and full-term pregnancy. Corpus luteum insufficiency means the corpus luteum does not produce the required levels of Progesterone.
This can cause:
- The endometrium to not thicken and vascularize, making it very difficult for implantation to take place.
- Affects the growth and development of the embryo in your early pregnancy.
And, these factors above can potentially lead to:
- Early miscarriage
- Fetal Demise
- Recurrent miscarriage*
*Corpus Luteum Insufficiney is a primary cause for a complex (multi-factor) recurrent miscarriages.
How does Hyperthyroidism cause recurrent immunological miscarriage?
We now understand that Hyperthyroidism will lead to corpus luteum insufficiency, leading to a miscarriage and potentially recurrent miscarriage during pregnancies.
If you have a history of miscarriages or fetal demise (induced abortion) caused by Hyperthyroidism. There is a high risk for you to develop recurrent immunological miscarriage.
After undergoing multiple D & C procedures, the fetal cells containing paternal genes may have entered the mother’s bloodstream. This triggers an immune reaction, generating anti-embryonic antibodies in the mother’s body. In subsequent pregnancies, the anti-embryonic antibodies readily attack the growing embryo, causing an inevitable miscarriage. This type of miscarriage is known as a recurrent immunological miscarriage.
Antai Hospital has patented and highly effective immunotherapy that can prevent future immunological RSA. Read more here.
Symptoms
- Swollen thyroid gland (in the neck area)
- Shorter menstrual period
- An increased amount of menses flow
- Loss of weight
- Mood swings and irritability
- Increased sweating
- Tiredness and muscle weakness
- Rapid or irregular heartbeat
Some adults may experience no or subtle symptoms (such as fatigue, loss of appetite, menstrual pattern change etc.), so it is vital to get checked today if you are worried or unsure.
Diagnosis
- A physical examination if there is a noticeable swelling of the thyroid gland.
- B-scan to check for the size and internal enlargement of the thyroid gland.
- A standard blood test to determine your T3 , T4 and TSH levels.
- Test for the presence of anti-embryonic antibodies.
Treatment at Antai Hospital
Antai Hospital will provide treatment for your Hyperthyroidism based on the following two conditions:
- If you are currently pregnant:
- Treatment of Hyperthyroidism (3 options)
- Surgically removed the excessive growths on the thyroid gland.
- Injection or oral administration of radioactive iodine is a common and effective treatment method.
- Antithyroid medication such as methimazole can also reduce the over-activity of the thyroid glands
- Treatment of Corpus Luteum Insufficiency (黄体支持)
- Here at Antai Hospital, we offer a progesterone supplement treatment that is personalized to your requirements. The dosage of Progesterone will be prescribed, specific, and accurate to your bodily needs. An overdose or underdose of Progesterone may lead to further complications*.
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Overdose of Pg: It will lead to difficulty for the placenta to detach from the endometrium as Pg’s increased levels will cause it to latch on deeper than usual.
Underdose of Pg: It will not resolve Corpus Luteum Insufficiency and still lead to fetal demise and early miscarriage.
- Immunity factors
- If you test positive for anti-embryonic antibodies, Antai will administer its patented immunotherapy that effectively prevents recurrent immunological miscarriage.
- If you are not pregnant (before pregnancy) :
- Treatment for Hyperthyroidism
- Surgically removed the excessive growths on the thyroid gland.
- Injection or oral administration of radioactive iodine is a common and effective treatment method.
- Antithyroid medication such as methimazole can also reduce the over-activity of the thyroid glands
- Immunity factors
- If you test positive for anti-embryonic antibodies, Antai will administer its patented immunotherapy that effectively prevents recurrent immunological miscarriage.
Antai Hospital is the only private hospital that offers patented and effective recurrent miscarriage treatment with full-refund policy. If you would like to find out more, please reach out to us via consultation or email to find out more.
Antai Hospital’s Commitment
Antai Hospital’s full refund policy for the miscarriage prevention treatments we provide should already be the best guarantee for a healthy pregnancy. Patients should rest assured, can and should go about their everyday life, focusing their diet on vegetables, beans, celery, and other fiber-rich foods. Besides that, an active lifestyle of yoga and swimming should also be incorporated to help relieve stress and increase blood circulation, which is beneficial for the fetus’s development and the mother’s health. With our assurance, a healthy lifestyle, and peace of mind, you can go through a healthy pregnancy with no complications.
Recurrent miscarriages are no doubt a heavy blow to the patient’s physical and mental health. All we can do is to help ease the burden and decrease your trauma, to slowly help you overcome the anxiety with the love and care that we provide at Antai Hospital.
Trust in Antai Hospital and trust in yourself, your pregnancy is our priority.