PCOS causes chronic hormonal imbalance and directly affects the development of the corpus luteum, egg cells and the endometrium for implantation, all of which causes negative complication for a pregnancy.
Why does Polycystic Ovarian Syndrome Cause Corpus Luteum Defect?
Having proper ovulation and releasing of mature eggs monthly are essential to the formation of a normal corpus luteum. However, PCOS is an endocrine disorder and people with PCOS have abnormal hormone levels that disrupts the ovarian follicles from growing and release mature eggs. The immature eggs in the follicles will thus affect the formation of corpus luteum, resulting in corpus luteum defect and low levels of progesterone. Polycystic ovarian syndrome (PCOS) is mainly caused by excessive androgens produced by the ovaries.
Symptoms of Polycystic Ovarian Syndrome
Some of the symptoms include:
- Irregular or no mensuration
- Obesity
- Acne on face and front & back of body
- Coarse body hair
Medical History
The more common medical history include:
- Infertility (due to irregular ovulation)
- Recurrent miscarriage (due to release of poor-quality eggs)
- Reproductive immunity disorder (a potential complication of PCOS and corpus luteum defect) can also be a contributing factor to recurrent miscarriage.
Diagnosis
There are several tests that can be done to diagnose PCOS.
- Blood Test. Patients with PCOS will have high levels of testosterone (T), low levels of follicle-stimulating hormones (FSH), and high levels of luteinizing hormone (LH)
- B-Scan. B-Scan can reveal if a patient has multiple ovarian follicles developing at the same time (多个卵泡同时发育). Normally, only one follicle will develop each month.
- 3D Laparoscopy. 3D laparoscopy can directly see if multiple ovarian follicles are developing at the same time and the development of the polycystic ovary.
Treatment of Polycystic Ovarian Syndrome and Corpus Luteum Defect
Both PCOS and corpus luteum defect must be properly treated in order to ensure a safe pregnancy.
PCOS: PCOS is mainly caused by the development of testicular tissues in the ovaries. Hence, Antai hospital treats PCOS by tackling the root cause and remove the testicular tissues via a 3D laparoscopic surgery.
Corpus Luteum Defect: For corpus luteum defect, the most worrying effect of the condition is having recurrent miscarriage due to low levels of progesterone. Hence, the most suitable treatment method is to supplement the level of progesterone. Antai hospital provides personalised treatment for each patient by calculating the level of progesterone each patient require. The calculation method is very accurate and ensures that the progesterone is not under or over supplemented. Administering just the sufficient amount of progesterone is very important because over supplementation might result in the embryo being lodged too deep into the lining of the uterus, while under supplementation will still lead to a miscarriage. Antai hospital offers contractual treatment with a full refund policy for unsuccessful treatment. Enquire with Antai today.