Cervical intra-epithelial neoplasia (CIN): Diagnosis & Treatment

Cervical intraepithelial neoplasia results from HPV infection within cervical cells. These changes, especially in young women, commonly revert to normal cells due to an intact immune response and rapid turnover of cells on the cervix. About 60% of CIN-1 will regress to normal after 1 year. Women with CIN-2 and CIN-3 are at high risk for developing invasive cancer, although the average time for progression is still several years. Therefore, women with CIN-2/3 should receive treatment. Exceptions to this recommendation are women in the 20 to 24 year age group and pregnant women.  Since a significant percentage of low-grade squamous intraepithelial lesions (LGSIL) on Pap smear will have CIN-2 or 3, it makes sense that these pap smears still require colposcopy and biopsy in most cases.

In most cases, CIN will subside on its own normally and naturally, however if you do need treatment, Antai Hospital provides effective treatment (安太液) in the removal of these abnormal cervical cells and fully prevents cancer from developing in the future. 

Causes of CIN

Human papillomavirus (HPV) infection of the cervix is a sexually transmitted disease and a significant risk factor for the development of cervical intraepithelial neoplasia.  However, only a relatively small percentage of women with the infection will develop severe CIN or invasive cervical cancer. Several factors determine whether the infection will progress to CIN or carcinoma, the greatest of which is the HPV genotype causing the infection. Although there are approximately 100 subtypes of HPV,  a small subgroup has a known association with cervical dysplasia and carcinoma.  HPV subtypes are considered either oncogenic or non-oncogenic.  Persistence of the virus in tissues is another critical factor in the development of CIN and ultimately, carcinoma.

The virus can live on the skin around the whole genital area. It passes easily from person to person during any type of sexual contact, including skin-to-skin genital contact or sharing sex toys. Using a condom or other barrier contraception may reduce your risk of HPV infection, but it does not offer complete protection.

Signs and symptoms of CIN

CIN and HPV do not cause any symptoms. It is important to have regular cervical screening tests to check for abnormal cell changes. If needed, these changes can be treated to prevent cancer.

Diagnosing CIN

The first part of cervical screening is a smear test. This does not show if you have CIN. But if your test result shows abnormal cells, you may then have a test called a colposcopy. The colposcopy shows abnormal areas of the cervix and how abnormal the cells are. It can be used to diagnose CIN and to decide if you need treatment.

There are 3 types of CIN:

CIN- I, CIN-II, CIN-III: The 1, 2 ,3 simply refers to the thickness of the cervical layer that is affected by the abnormal cells. For CIN 1, ⅓ has been affected. For CIN 2, ⅔ has been affected. For CIN 3, 3/3 has been affected.

Treatment of CIN

Antai Hospital’s proprietary medication 安太液,treats and removes the CIN from the affected regions of your cervix. During the treatment, our doctors apply it carefully to ensure abnormalities are effectively removed, and prevents future recurrence. This treatment is equally effective for CIN 1, CIN 2 AND CIN 3, and comes with a full refund guarantee policy, our moneyback guarantee.

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