The immune system makes an abundance of proteins called antibodies. Antibodies are made by white blood cells (B cells). The antibodies recognize and combat infectious organisms (germs) in the body. Antibodies develop in our immune system to help the body fight infectious organisms. When an antibody recognizes the foreign proteins of an infectious organism, it recruits other proteins and cells to fight off the infection. This cascade of attack is called inflammation.
Sometimes these antibodies make a mistake, identifying normal, naturally occurring proteins in our bodies as being “foreign” and dangerous. When these antibodies make incorrect calls, identifying a naturally occurring protein (or self-protein) as foreign, they are called autoantibodies. Autoantibodies start the cascade of inflammation, causing the body to attack itself. The antibodies that target “normal” proteins within the nucleus of a cell are called antinuclear antibodies (ANA).
Anti-embryonic antibodies (Ae-Ab) are known as anti-nuclear antibodies (ANAs) that are generated by the maternal immune system when it encounters foetal tissues within the circulatory system. Foetal tissues contain paternal genes, which are considered foreign to the mother, which causes the immune system to react in a defensive manner. Thus, these antibodies are created. Specifically, these antibodies attack a specific chromosome (chromosome 2) contained within foetal cells.
Chromosome 2 inside growing foetal cells, are responsible for the secretion and production of an important protein that functions to protect the pregnancy from being in contact directly with the mother’s environment, protecting it from a potential immune response. This protein forms a layer that is the fibronectin layer, which serves as an immunological barrier to protect the foetus. Those that develop these antibodies, can cause disruption or complete absence of this protective barrier. This inevitable leads to an immuno-miscarriage, and if left untreated and allowed to happen repeatedly, it will become known as recurrent immunological miscarriage. Women who have a hisotry of recurrent miscarriages, very likely carry these antibodies.
What can cause you to develop these antibodies?
- Induced Abortions (67%)
- Unexplained infertility (possible indication of chemical pregnancies)
- Multiple failed IVFs
- Childbirth (C-section or Natural birth)
- Engaging in intercourse during menses period
These factors allow the introduction of foetal cells containing paternal genes into the mother’s bloodstream, unknowingly allowing the mother to develop these antibodies. It is especially easy for a mother to develop these antibodies via induced abortions, where during the scrapping process, it exposes uterine veins that can carry small, shattered fetal tissues into her bloodstream.
Antai Hospital’s Immunotherapy to counteract the antibody reaction.
Antai’s immunotherapy is a gene vaccine that is administered via intravenous injections, and effectively neutralises the anti-embryonic antibodies. Before receiving the injections, you will be tested for the presence and levels of the antibodies. You are highly recommended to be tested for anti-embryonic antibodies if you have a history of recurrent miscarriage or have undergone an induced abortion procedure before. Otherwise, you may also opt to get tested for self-assurance.
This treatment comes with a full refund guaranteed, and ensures a successful pregnancy. If you do test negative for anti-embryonic antibodies, then we will further proceed with further diagnosis to accurately assess and determine the cause/causes of your recurrent miscarriage and unexplained infertility depending on whether it is single-factor or multiple factors.